Instead, you must worship Christ as Lord of your life. And if someone asks about your Christian hope, always be ready to explain it. - 1 Peter 3:15 NLT
Here is a fantastic definition of what a premise is:
A premise is the assumption of an argument that is meant to justify the conclusion the one making the argument is hoping you’ll come to. If one fails to establish the premise to his argument, one almost always fails to convince others of his conclusion. On the other hand, if one establishes a premise one will more than likely get others to agree with his conclusion. - from the article, "Never Accept the Premise of Your Opponent’s Argument" by Steve Deace, Townhall.com
We want to do what Jesus did and change or correct the premise of questions we get asked, to what should have been asked to lead to salvation. Jesus did this many times. Let's become expert in delivering the gospel and become expert in rephrasing questions about life and give context to a topic so the truth can be established.
The teaching of your word gives light, so even the simple can understand. - Psalm 119:130 NLT
The premise in the questions we use to deliver the Gospel or teach the scriptures, should speak toward salvation and understanding the Lord. They should steer away from conversations that devolve into confusion.
This is an integral tool to delivering the gospel at every opportunity and creating an opportunities where it may not seem to exist.